A new breakthrough in bioprinting, called Deep tissue In vivo Sound Printing (DISP), allows doctors to create 3D structures directly inside the body without any incisions. Instead of using the traditional nozzle based 3D printer, this method uses a simple injection of a specially designed bio-ink followed by focused ultrasound beams. These sound waves heat the targeted area by just a few degrees, which causes tiny fat-based capsules liposomes inside the ink to burst and release chemicals that instantly turn the liquid into a soft, biocompatible gel. Using ultrasound imaging, researchers can precisely control the shape, depth, and placement of these structures, even several centimeters below the skin. In tests with animals, the team successfully printed drug-releasing structures near tumors and created tissue scaffolds inside muscle, showing both effectiveness and safety. The printed gels can even be removed later with a harmless chemical. Unlike earlier in-body printing attempts that caused overheating or tissue damage, DISP avoids these problems, making it a promising new direction for minimally invasive treatments in cancer therapy, tissue engineering, and bioelectronics.
Read more-https://spectrum.ieee.org/bioprinting-inside-the-body